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1996-02-27
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Document 0665
DOCN M9630665
TI A controlled study of anxiety and morbid cognitions at initial screening
for human immunodeficiency virus (HIV) in a cohort of people with
haemophilia.
DT 9603
AU Jones QJ; Garsia RJ; Wu RT; Job RF; Dunn SM; Medical Psychology Unit,
University of Sydney, Australia.
SO J Psychosom Res. 1995 Jul;39(5):597-608. Unique Identifier : AIDSLINE
MED/96058809
AB AIM. This study examines the relationship between anxiety, psychological
state and Human Immunodeficiency Virus (HIV) stages as defined by the
Centers for Disease Control at the time of initial screening for HIV in
a cohort of people with haemophilia who were at risk of prior exposure
to HIV transmission from blood products. METHOD. Psychological scores,
immunological measures, and clinical data from case notes for 116
potentially HIV exposed people with haemophilia attending initial
screening for HIV infection in 1984-1985, were used to examine the
relationship between psychological variables, clinical state and their
clinical classification under the Centres for Disease Control
categorization. Psychometric test results were obtained for 63 HIV
seronegative patients and 53 HIV seropositive patients. Planned
comparisons, multiple and logistic regressions, were used to explain
observed differences between seronegative and seropositive subjects. The
potential confounders of sex, age, severity of haemophilia, haemophilia
type and blood product usage were controlled. RESULTS. The major finding
of this study was that higher levels of State Anxiety at the time of
initial screening for HIV, were observed in those patients who lacked
recognized symptoms of HIV infection and were seropositive, compared
with seronegative subjects. The State Anxiety scores were predicted by
HIV infection or alternatively CD4+ T-cell levels. CONCLUSION. The
findings of this study suggest that HIV infection can produce
psychological effects prior to any physical symptoms of infection being
apparent.
DE von Willebrand's Disease/*PSYCHOLOGY Adult Anxiety/*PSYCHOLOGY
*Attitude to Health AIDS Serodiagnosis/*PSYCHOLOGY Blood Component
Transfusion/PSYCHOLOGY Christmas Disease/*PSYCHOLOGY Female
Hemophilia/*PSYCHOLOGY Human HIV Infections/*PSYCHOLOGY/TRANSMISSION
HIV Seronegativity HIV Seropositivity/PSYCHOLOGY Male Mass
Screening/*PSYCHOLOGY Risk Factors JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).